The long-standing discipline of process improvement has reemerged as a central concern for organizations as they continue in their automation and digital transformation efforts. In the realm of T&E expense management, much of the concern for process improvement and optimization has focused on the reimbursement process. So the question “What does a T&E expense reimbursement best-practice process look like?” is easy to answer but somewhat involved to carry out. Leading organizations have applied core process improvement tenets, standardized an effective approach, found a cloud-based tool to streamline the workflow, and continue to refine elements in order to continually advance process maturity. This article summarizes characteristics of a best-practice T&E process from the secondary research.